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Medical Microneedling in Irvine

Medical Microneedling in Irvine

Not all microneedling is the same. In California, microneedling is legally classified as a medical procedure that can only be performed by a licensed physician or supervised medical professional. At RH Medical & Wellness Center in Irvine, Dr. Roya Hormozdiaran performs every treatment personally, combining medical-grade Dermapen 4 technology with clinical precision for results that go well beyond what a spa setting can offer.

What is medical microneedling?

Collagen induction therapy - How it works

Who this care is for

Medical microneedling, also known as collagen induction therapy (CIT), uses a precision device to create thousands of controlled micro-channels in the skin. This triggers the body’s natural healing response, stimulating the production of new collagen and elastin. The result is gradual, visible improvement in skin texture, tone, and firmness that continues for months after each session.

At RH Medical & Wellness Center, we use the Dermapen 4 (DP4), creating 1,920 micro-channels per second with adjustable depth precision. This level of control is what separates a clinical treatment from a standard spa procedure.

Medical microneedling, also known as collagen induction therapy (CIT), uses a precision device to create thousands of controlled micro-channels in the skin. This triggers the body’s natural healing response, stimulating the production of new collagen and elastin. The result is gradual, visible improvement in skin texture, tone, and firmness that continues for months after each session.

At RH Medical & Wellness Center, we use the Dermapen 4 (DP4), creating 1,920 micro-channels per second with adjustable depth precision. This level of control is what separates a clinical treatment from a standard spa procedure.

Microneedling with Dermapen 4 on a woman face

What medical microneedling can treat

Conditions and skin concerns

Fine lines and wrinkles

Fine lines and wrinkles

Acne scars and post-inflammatory marks

Acne scars and post-inflammatory marks

Enlarged pores

Enlarged pores

Uneven skin tone and texture

Uneven skin tone and texture

Sun damage and hyperpigmentation

Sun damage and hyperpigmentation

Dull or dehydrated skin

Dull or dehydrated skin

Early signs of skin laxity

Early signs of skin laxity

Fine lines and wrinkles

Acne scars and post-inflammatory marks

Enlarged pores

Uneven skin tone and texture

Results are gradual and cumulative. Most patients see initial improvement within 2 to 4 weeks, with full collagen remodeling continuing for up to 3 months after each session.

Medical-grade microneedling under physician supervision

Why choose a physician over a med Spa

Physician-performed microneedling means your treatment depth, speed, and approach are determined by a clinician with full knowledge of your health history, not by a technician following a standard protocol.

Physician-performed microneedling means your treatment depth, speed, and approach are determined by a clinician with full knowledge of your health history, not by a technician following a standard protocol.

Every session is performed personally by Dr. Roya Hormozdiaran, Board Certified Internist with 20+ years of clinical experience, who evaluates your skin condition and adjusts treatment parameters to your specific needs

Every session is performed personally by Dr. Roya Hormozdiaran, Board Certified Internist with 20+ years of clinical experience, who evaluates your skin condition and adjusts treatment parameters to your specific needs

Treatment depth and needle speed are calibrated based on your skin type, sensitivity, and the concern being addressed

Treatment depth and needle speed are calibrated based on your skin type, sensitivity, and the concern being addressed

Dermapen 4 is an FDA-cleared medical-grade microneedling device used in clinical and research settings worldwide

Dermapen 4 is an FDA-cleared medical-grade microneedling device used in clinical and research settings worldwide

Your full medical history, current medications, and any contraindications are reviewed before every session

Your full medical history, current medications, and any contraindications are reviewed before every session

Any contraindications, skin conditions, or medications that may affect treatment safety are reviewed before each session

Any contraindications, skin conditions, or medications that may affect treatment safety are reviewed before each session

Your treatment plan and outcomes are documented in your medical record and reviewed at follow-up visits

Your treatment plan and outcomes are documented in your medical record and reviewed at follow-up visits

"When microneedling is performed with the right depth, the right device, and a clear understanding of your skin’s needs, the results speak for themselves."
- Dr. Roya Hormozdiaran, MD

"When microneedling is performed with the right depth, the right device, and a clear understanding of your skin’s needs, the results speak for themselves."
- Dr. Roya Hormozdiaran, MD

Enhanced with exosomes

Beyond collagen stimulation

For patients who want to take results further, we offer exosome therapy as an enhancement to standard microneedling. Exosomes are microscopic regenerative messengers that carry growth factors and cellular renewal signals directly into the skin through the micro-channels created during treatment.

A single oscillation of the Dermapen 4 needle cartridge can deliver 112,000 exosomes into the skin. Clinical studies show pore reduction of up to 41% at 5.5 months, with results maintained at 21 months after just 2 sessions when combining Dermapen 4 with exosomes.

Exosome enhancement accelerates healing, reduces inflammation, and guides the skin’s repair process at a cellular level, producing results that last significantly longer than microneedling alone.


Ask Dr. Roya at your consultation whether exosome therapy is right for your skin concern.

Your treatment at RH Medical & Wellness Center

What to expect at your session

Each session at RH Medical & Wellness Center includes:

A personalized skin assessment with Dr. Roya before treatment

A personalized skin assessment with Dr. Roya before treatment

Topical numbing for comfort during the procedure

Topical numbing for comfort during the procedure

Dermapen 4 treatment with depth calibrated to your skin type and concern

Dermapen 4 treatment with depth calibrated to your skin type and concern

Post-treatment guidance and a skincare protocol to protect and extend your results

Post-treatment guidance and a skincare protocol to protect and extend your results


Sessions are 45 to 60 minutes. Most patients experience mild redness for 24 to 48 hours with minimal downtime.


How many sessions do you need?

For most skin concerns, a series of 3 sessions spaced 4 to 6 weeks apart produces the most significant results. Maintenance sessions every 6 to 12 months help sustain collagen levels over time.

Limited Offer
3-Session Package

Limited Offer
3-Session Package

Fall is the ideal time to start a microneedling series - cooler weather supports skin recovery and sun exposure is reduced. For a limited time, we are offering a discounted 3-session package performed personally by Dr. Roya Hormozdiaran, Board Certified Internist.

Call (949) 222-0009

Limited availability. New patients welcome.

Ready to achieve a better you?

Schedule your next visit through our secure patient portal. Whether you are a returning patient or joining our Irvine practice for the first time, we look forward to supporting your health journey.

Book an appointment

Book an appointment

Ready to achieve a better you?

Schedule your next visit through our secure patient portal. Whether you are a returning patient or joining our Irvine practice for the first time, we look forward to supporting your health journey.

Book an appointment

Book an appointment

Frequently asked questions

Below are answers to the questions we hear most often from patients in Irvine and Orange County considering medical microneedling for the first time.

Who is not a suitable candidate for microneedling?

Is Dermapen 4 microneedling safe for all skin types?

How long do microneedling results last?

Does microneedling hurt?

Is numbing cream required before microneedling?

How many sessions do I need to see results?

Can I wear makeup after microneedling?

What are exosomes and why are they used with microneedling?

What serums are used during the microneedling treatment?

Frequently asked questions

Below are answers to the questions we hear most often from patients in Irvine and Orange County considering medical microneedling for the first time.

Who is not a suitable candidate for microneedling?

Is Dermapen 4 microneedling safe for all skin types?

How long do microneedling results last?

Does microneedling hurt?

Is numbing cream required before microneedling?

How many sessions do I need to see results?

Can I wear makeup after microneedling?

What are exosomes and why are they used with microneedling?

What serums are used during the microneedling treatment?

Frequently asked questions

Below are answers to the questions we hear most often from patients in Irvine and Orange County considering medical microneedling for the first time.

Who is not a suitable candidate for microneedling?

Is Dermapen 4 microneedling safe for all skin types?

How long do microneedling results last?

Does microneedling hurt?

Do I need a referral to see Dr. Roya for hormone or menopause care in Irvine?

How many sessions do I need to see results?

Can I wear makeup after microneedling?

What are exosomes and why are they used with microneedling?

What serums are used during the microneedling treatment?